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Microfluidic cartridge development
CSEM SA
CSEM is a privately held, R&D center established in 1984 in Neuchâtel, Switzerland. From the beginning, CSEM has been committed to both applied and order-related R&D. This bridge function between economics and science is still a core aspect of the company, and CSEM has continuously adapted its research areas to the needs of industry.
MedPhab partner
[TECHNICAL] DEVELOPMENT SUPPORT
Development Support
DEVELOPMENT SUPPORT [System design] Microfluidics / Mechanical design
[System design] Microfluidics / Mechanical design
in vitro diagnostics in vivo diagnostics therapeutics others
Technology provider Supplier Manufacturer Production services Integrator R&D Clinical
At CSEM we have developed a disposable microfluidic cartridge to pretreat whole blood to plasma which is then analysed on a bio-photonic chip with on-cartridge valves, on-cartridge reservoirs and on-cartridge pumps. With the cartridge we also designed a corresponding instrument. The cartridge had been prototyped at CSEM and finally outsourced for injection moulding. All the characterization has been done at CSEM like imaging, leaktest, laser scanning microscopy...
On-cartridge liquid storage yes - syringe or blister
Liquid movement principle on-cartridge syringe
CAD Software Solidworks (3D) and Draftsight (2D)
On-cartridge valve yes
On-cartridge pump yes - syringe or blister
Sample preparation whole blood to plasma
Detection method Anti-body binding assay which induces refractive index change via an aMZI
Sample size 150 ul
Material PC
Coating to reduce nonspecific binding yes
At CSEM we have developed a disposable microfluidic cartridge to pretreat whole blood to plasma which is then analysed on a bio-photonic chip with on-cartridge valves, on-cartridge reservoirs and on-cartridge pumps. With the cartridge we also designed a corresponding instrument.
CSEM DS2 0001 V1.0
ISO 9001
Typically up to 100 cartridge (credit-card sized) per month depending on task complexity